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http://ir.futminna.edu.ng:8080/jspui/handle/123456789/10844| Title: | Acute Toxicity Studies of Extract of Cussonia barteri in Rats |
| Authors: | Shamaki, B. U. Iliyasu, B. Abubakar, A. Onyekwelu, N. A. |
| Keywords: | Cussonia bateri, Toxicity, rats |
| Issue Date: | 2003 |
| Publisher: | The Nigerian Veterinary Medical Association |
| Citation: | Shamaki et al, 2003 |
| Abstract: | Acute toxicity studies of the aqueous extract of Cussonia barteri (c.b) which was reported to be of therapeutic value in the management of many diseases including trypanosomosis was evaluated in rats. Animal treated with doses of 1000 - 5000 mg/kg showed such symptoms of toxicity as piloerection, scratching of the mouth and dyspnoea. Gross pathological lesions observed include slightly congested lungsand liver and gastric impaction. The median lethal dose (LD50) of the C. barteri aq extract was calculated to ba 2,500 mg/kg bodyweight and this study has confirmed that the plant extract is slightly toxic. |
| URI: | http://repository.futminna.edu.ng:8080/jspui/handle/123456789/10844 |
| Appears in Collections: | Biochemistry |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Nigeria Veterinary Journal.pdf | 1.88 MB | Adobe PDF | View/Open |
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