Using Shanchol Oral Vaccines To Prevent Cholera In children Under Five Years Of Age: A Deterministic Modeling Approach.

Abstract

Cholera epidemic remains a global threat to public health and a key indicator of lack of social development in most part of third world countries. Cases tend to be clustered by location as well as season, with most infections occurring in children ages 1-5 years. This research provides new mathematical deterministic compartmental models for preventive cholera transmission dynamics, using Shanchol Oral Vaccines for under five years age. These models were built on SIR and vibrio cholera (B) models .The transmission means; global impact and preventive mechanism of disease are discussed. We establish the Disease free and the endemic equilibrium states, and carried out the stability analysis of the Disease free equilibrium. It is shown that the model disease free equilibrium is locally and globally stable in as much we keep value of T < 0 and D > 0 (the state of complete eradication of cholera from entire population).