A Mathematical Model Analysis of Meningitis with Treatment and Vaccination in Fractional Derivatives

Abstract

In this paper, we develop a new mathematical model based on the Atangana Baleanu Caputo (ABC) derivative to investigate meningitis dynamics. We explain why fractional calculus is useful for modeling real-world problems. The model contains all of the possible interactions that cause disease to spread in the population. We start with classical differential equations and extended them into fractional-order using ABC. Both local and global asymptotic stability conditions for meningitis-free and endemic equilibria are determined. It is shown that the model undergoes backward bifurcation, where the locally stable disease-free equilibrium coexists with an endemic equilibrium. We also find conditions under which the model’s disease-free equilibrium is globally asymptotically stable. The approach of fractional order calculus is quite new for such a biological phenomenon. The effects of vaccination and treatment on transmission dynamics of meningitis are examined. These findings are based on various fractional parameter values and serve as a control parameter for identifying important disease-control techniques. Finally, the acquired results are graphically displayed to support our findings.