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http://ir.futminna.edu.ng:8080/jspui/handle/123456789/16394| Title: | Effect of Guiera senegalensis Leaf Extract on Some Echis carinatus Venom Enzymes |
| Authors: | A.B, Sallau G.C, Njoku A.R, Olabisi A.U, Wurochekke Abdullahi, Abdulkadir Shehu, Isah M.S, Abubakar S, Ibrahim |
| Keywords: | Guiera senegalensis Leaf ,Echis carinatus Venom Enzymes |
| Issue Date: | 2005 |
| Publisher: | Journal of Medical Sciences |
| Citation: | A.B. Sallau, G.C. Njoku, A.R. Olabisi, A.U. Wurochekke, A.A. Abdulkadir, Shehu Isah, M.S. Abubakar and S. Ibrahim, 2005. Effect of Guiera senegalensis Leaf Extract on Some Echis carinatus Venom Enzymes. Journal of Medical Sciences, 5: 280-283. |
| Series/Report no.: | 10.3923/jms.2005.280.283; |
| Abstract: | Aqueous extract of Guiera senegalensis leaves was investigated for the inhibitory action on the activity of crude phospholipase and metalloprotease enzymes from Echis carinatus venom. Both enzymes were inhibited by the extract in a dose dependent fashion. Double reciprocal plots of the initial velocity data of the inhibition by the extract revealed a non-competitive pattern of inhibition for the metalloprotease and a competitive one for the phospholipase. Extrapolated Ki values were found to be 11.9 and 90 μg mL-1 for the metalloprotease and phospholipase, respectively. |
| URI: | http://repository.futminna.edu.ng:8080/jspui/handle/123456789/16394 |
| Appears in Collections: | Biochemistry |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 280-283 X.pdf | 294.66 kB | Adobe PDF | View/Open |
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