Some Serum Biochemical and Haematological Changes in Experimental Trypanosoma brucei infection of Rabbits

Abstract

Serum Biochemical and haematological changes were studied for five consecutive weeks in male adult rabbits experimentally infected sub-cutaneously with T.b. brucei. They were treated with berenil 3 weeks post infection. The infection produced significant decrease in mean PCV, Hb and RBC count values (p<0.05). There were significant elevation of mean total serum protein between 2 - 3 weeks and mean alkaline phosphatase at week 3 post infection (p<0.05). Following treatment with berenil all these parameters return to control level after 2 weeks. No significant change was change was found in acid phosphatase activities (p>0.05). The implication of these results are briefly discussed.