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http://ir.futminna.edu.ng:8080/jspui/handle/123456789/6609| Title: | In-vitro antibacterial activity-guided isolation and characterization of beta-sitosterol from the mesocarp of the fruits of Diospyros mespiliformis |
| Authors: | FADIPE, Labake Ajoke Babayi, H. Ogunyemi, O. J. Suleiman, B. O. Yahaya, J Agada, E. E. Anga, P. I. |
| Keywords: | Antibacterial, β-sitosterol, chloroform extract, Diospyros mespiliformiis, isolation and mesocarp |
| Issue Date: | 12-May-2017 |
| Publisher: | Book of Proceedings of 1st SPS Biennial Conference held at FUT Minna, Niger State, Nigeria from 4th - 5th May, 2017, pp. 787 - 796. |
| Citation: | FADIPE, L. A, Babayi, H., Ogunyemi, O. J., Suleiman, B. O., Yahaya, J, Agada, E. E. & Anga, P. I. (2017). In-vitro antibacterial activity-guided isolation and characterization of beta-sitosterol from the mesocarp of the fruits of Diospyros mespiliformis. Book of Proceedings of 1st SPS Biennial Conference held at FUT Minna, Niger State, Nigeria from 4th - 5th May, 2017, pp. 787 - 796. |
| Series/Report no.: | 1; |
| Abstract: | A phytochemical and antibacterial study of te chloroform extract of the mesocarp of the fruits of Diospyros mespiliformis and its fractions led to the isolation of β-sitosterol (a phytosterol) for the first time from the fruits of the plant. The structure of the isolated compound was elucidated using physical parameters, colour reactions, spectroscopic identification and literature search. The isolated compound at 100 µg/cm3 dosplayed moderate inhibitory activity against tested Gram-positive and Gram-negative organisms in comparison to that exhibited by erythromycin (100 µg/cm3) against the testorganisms. |
| URI: | http://repository.futminna.edu.ng:8080/jspui/handle/123456789/6609 |
| Appears in Collections: | Chemistry |
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| National 5.pdf | 2.33 MB | Adobe PDF | View/Open |
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