Synthesis, Spectroscopic And Inhibitory Study Of Some Substituted Schiff Bases

Abstract

A series of Schiff bases namely (E)-4-methoxy-2-((phenylimino)methyl)phenol [I], (E)-2-(((4- chlorophenyl)imino)methyl)-4-methoxyphenol [II], (E)-2-(((2-hydroxyphenyl)imino)methyl)-4-methoxyphenol [III], (E)- 2-(((5-chloro-2-methylphenyl)imino)methyl)-4-methoxyphenol [IV] derived from substituted aniline and 5- methoxysalicylaldehyde were synthesized and characterized by elemental analysis, IR, UV, and 1H NMR. The results revealed that the compounds are capable to prevent the growth Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa, Streptococcus agalactiae, Staphylococcus aureus and Salmonella typhimurium in diverse concentrations. The growth prevention capability was affected by the substituent on the aniline.